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KMID : 0356620020170050698
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Journal of Korean Society of Endocrinology
2002 Volume.17 No. 5 p.698 ~ p.704
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A Case of Cerebral Salt Wasting Syndrome associated with Tuberculous Meningitis
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Rho Seung-Hyuk
Choi Ji-Yong
Nam Taek-Man
Kim Hyeon-Kyu
Lee Seong-Jin
Jeong In-Kyung
Hong Eun-Gyoung
Choi Cheol-Soo
Kim Doo-Man
Ihm Sung-Hee
Yoo Jae-Myung
Choi Moon-Gi
Yoo Hyung-Joon
Park Sung-Woo
Kim Hyoung-Cheol
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Abstract
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Hyponatremia in patients with central nervous system disorders is suggestive of the syndrome of inappropriate secretion of antidiuretic hormone (SIADH), and volume restriction is recommended for its correction. However, if volume depletion is present in a situation otherwise compatible with SIADH, cerebral salt wasting syndrome (CSWS) should be considered as the cause of the hyponatremia to avoid hypovolemic shock that may be induced by the standard management of SIADH, i.e. volume restriction. We present a case of a 17-year-old male patient with CSWS associated with tuberculous meningitis. The clinical feature of the patient comprised hyponatremia, excessive natriuresis, polyuria, and hypovolemia. Following the administration of saline and fludrocortisone, natriuresis and polyuria were decreased, and the hyponatremia improved.
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KEYWORD
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Cerebral salt wasting syndrome, Tuberculous meningitis, Hyponatremia
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